Manitoba First Nations Police Service (MFNPS) continues to search for leads in a missing woman case that spans over two decades.

Mary Lisa Smith, a community member from Roseau River First Nation, was reported missing to the former Dakota Ojibway Police Service on August 8, 1999. Police say family members became concerned after Smith discharged herself from the Selkirk Mental Health Centre.

According to MFNPS, it's believed that Smith may have suffered head trauma from a prior assault 4 years earlier in 1995. The 25-year-old was also suffering from Schizophrenia which required medication.

Police say reports filtered in that Smith may have travelled to Vancouver but were never confirmed.

At the time of her disappearance, Smith is described as 4'10" tall and approximately 90-95 lbs, with shoulder-length brown hair, brown eyes, and known to wear glasses. She was a mother of four at the time.

Smith also has tattoos described as a unicorn on her left hand, a flower on her right hand that is possibly a poinsettia or an orchid, and a heart on her upper right arm.

Since her disappearance police say there has been no confirmed contact from Smith, and her family and police continue to be concerned for her safety and well-being as it is uncommon for Smith to not have contact with her family.

If you have any information on the whereabouts and well-being of Mary Lisa Smith, please contact Manitoba First Nations Police Service, Criminal Investigators Unit at 204-856-5370, or Crimestoppers at 1-800-222-TIPS (8477).