One person is in hospital following a fire Saturday morning on Main Street.

Fire crews responded to a two-storey commercial and residential, mixed-use building in the 800 block of Main Street at 7:19 a.m. 

When crews arrived at the scene, they found heavy smoke and flames coming from the building. Due to the advanced fire conditions and a risk of collapse, crews launched a fire attack from the exterior, using handlines and aerial ladder trucks to apply water to the fire.

Everyone in the building self-evacuated before fire crews arrived. One person was transported to hospital in stable condition.

Due to drifting smoke, crews are currently evacuating a neighbouring high-rise as a precaution. Residents living with disabilities are being helped out of the building by firefighters.

This is anticipated to be a prolonged incident, and crews are expected to remain on scene throughout the day.

Winnipeg Transit has deployed buses to the scene to shelter evacuees. 

Main Street is closed in both directions between Higgins Avenue and Dufferin Avenue. Residents are asked to avoid the area, and motorists are advised to take alternate routes to get to their destinations. 

The cause of the fire is under investigation. Damage estimates are not available; however, the building will be a complete loss.