Westbound Goulet Street at Marion Street is now open.
Drivers are being asked to avoid a road that will be partially closed for at least 24 hours.
The Winnipeg Police Service says westbound Goulet Street at Marion Street is closed and will be for the next day.
In an initial tweet, they said the lanes would be closed due to a hazardous material spill until 4 p.m. Thursday, but that has since changed.
"Closure is now expected to last 24h. Please plan your trip accordingly," they said.