Parts of Manitoba are once again preparing for a significant late spring storm. 

Environment Canada says a large-scale trough of low pressure extending northward from a Colorado Low in the northern plains of the United States will lead to a prolonged period of precipitation in the southern Prairies.

Precipitation will likely be mixed at times with rain, especially over south-central Manitoba. Currently, anywhere from 10 to 20 centimetres of snow is expected in parts of western Manitoba from the Saskatchewan Border to as far east as Headingley. The highest confidence for the heaviest precipitation lies over eastern Saskatchewan and western Manitoba, roughly from Regina to the Manitoba Parklands.

Meteorologists say there are several uncertainties and complicating factors that remain to be determined with the system. 

The greatest uncertainty lies over western Saskatchewan, west of Regina, and the Red River Valley, east of Portage la Prairie in Manitoba.

It's believed that the system will roll in overnight on Tuesday into Wednesday for most regions, with some areas seeing over 20 mm of all types of precipitation, increasing flood risks for some regions. 

The system will also bring strong winds to the area, leading to poor travel conditions on Wednesday. 

The City of Winnipeg is currently not under a special weather advisory. However, snow and rain are expected about mid-week.